Experimental AIDS vaccine made volunteers more susceptible to HIV

[w¡n9Nµ7 §£@¥€r 123]

AIDS vaccine researchers are worried about the future of their field after learning an experimental HIV vaccine not only does not work, but just might make recipients more susceptible to infection with the AIDS virus.

They are worried about their volunteers and the future of AIDS vaccines in general. And they are worried because they cannot understand how a vaccine would make a person more vulnerable.

Researchers from Merck & Co., which makes the vaccine, and the National Institute of Allergy and Infectious Diseases, which is helping develop it, said on Wednesday they believe a type of common cold virus used as the basis of the vaccine may somehow have made their volunteers more susceptible to HIV.

They are meeting this week in Seattle to hash through the data and figure out what happened.

This is what they know: Out of 1,500 people vaccinated, 82 became infected with the AIDS virus. Of these, 49 got the vaccine and 33 got a placebo shot.

While they are counseling volunteers that they may have raised their own risk of becoming infected, they are also trying to figure out what happened.

"The data are disappointing and puzzling but we don't have definitive answers," Dr. Lawrence Corey of Fred Hutchinson Cancer Research Center in Seattle, who was organizing the trial, told reporters.

Only one woman in the trial became infected with HIV. The rest were men having sex with other men, and it was the men who started out with the highest immune response to the adenovirus 5 common cold bug used to make the vaccine who were the most likely to become infected with the AIDS virus.

But the infected men were also less likely to have been circumcised -- circumcision can also prevent HIV infection -- and may have engaged in more risky behavior. So did the vaccine actually do something, or were the results a fluke?

"I don't think we really do know," Dr. Keith Gottesdiener of Merck Research Laboratories told Reuters.

http://www.reuters.com/article/newsOne/idUSN0822615120071108

[Hilarious Clinton 452]

Only one woman in the trial became infected with HIV. The rest were men having sex with other men,

http://www.reuters.com/article/newsOne/idUSN0822615120071108

vaccine made volunteers more susceptible to HIV. No... it was the gay sex. duh

[w¡n9Nµ7 §£@¥€r 123]

Only one woman in the trial became infected with HIV. The rest were men having sex with other men,

http://www.reuters.com/article/newsOne/idUSN0822615120071108

vaccine made volunteers more susceptible to HIV. No... it was the gay sex. duh

Did you notice this little tidbit hidden inside the article?

... circumcision can also prevent HIV infection ...

[Welshcookie 17]

"I don't think we really do know," Dr. Keith Gottesdiener of Merck Research Laboratories told Reuters.

http://www.reuters.com/article/newsOne/idUSN0822615120071108

Thanks...that was really helpful

[w¡n9Nµ7 §£@¥€r 123]

"I don't think we really do know," Dr. Keith Gottesdiener of Merck Research Laboratories told Reuters.

http://www.reuters.com/article/newsOne/idUSN0822615120071108

Thanks...that was really helpful

At least it's honest.

[cuteprince 0]

AIDS vaccine researchers are worried about the future of their field after learning an experimental HIV vaccine not only does not work, but just might make recipients more susceptible to infection with the AIDS virus.

VJ Troll

I never undersood why would you post these messages here all the time this is not a news forum the purpose of this forum is to discuss about Visa.

Edited November 10, 2007 by cuteprince

[Hilarious Clinton 452]

VJ Troll

I never undersood why would you post these messages here all the time this is not a news forum the purpose of this forum is to discuss about Visa.

This is OFF-TOPIC.

topic = family based immigration

off-topic = everything else

any questions?

[Ban Hammer 14,571]

VJ Troll

I never undersood why would you post these messages here all the time this is not a news forum the purpose of this forum is to discuss about Visa.

This is OFF-TOPIC.

topic = family based immigration

off-topic = everything else

any questions?

gotta love ot newbies

[Mel_and_Daniel 1]

But the infected men were also less likely to have been circumcised -- circumcision can also prevent HIV infection

http://www.reuters.com/article/newsOne/idUSN0822615120071108

Only one woman in the trial became infected with HIV. The rest were men having sex with other men,

http://www.reuters.com/article/newsOne/idUSN0822615120071108

vaccine made volunteers more susceptible to HIV. No... it was the gay sex. duh

Did you notice this little tidbit hidden inside the article?

... circumcision can also prevent HIV infection ...

Another tidbit

They also pretend that they do not know whether the men were circumcised. They must really be at a loss...

[sj5 4]

VJ Troll

I never undersood why would you post these messages here all the time this is not a news forum the purpose of this forum is to discuss about Visa.

This is OFF-TOPIC.

topic = family based immigration

off-topic = everything else

any questions?

good grip

[almaty 19]

VJ Troll

I never undersood why would you post these messages here all the time this is not a news forum the purpose of this forum is to discuss about Visa.

This is OFF-TOPIC.

topic = family based immigration

off-topic = everything else

any questions?

gotta love ot newbies

sheesh noobs

[Nagishkaw 510]

She was trying to tell The Persian Shoe in a nice way to STFU.

[almaty 19]

She was trying to tell The Persian Shoe in a nice way to STFU.

sister, i know..the noob over-stepped her role.

[Jasman0717 9]

This whole aids thing is very scary

[Welshcookie 17]

She was trying to tell The Persian Shoe in a nice way to STFU.

sister, i know..the noob over-stepped her role.