Humans Not As Genetically Identical As We Thought

[Danno 1,228]

Humans Not As Genetically Identical As We Thought

What’s previously been taught is that of the 6 billion or so people on the planet, we all share 99.9% of each others genes and identity. These results came from the Human Genome Project 5 years ago and are now assumed to be very much wrong. Today, research was published in the journal Nature and ABC Science News reports that we are genetically more varied than what was once assumed.

The analysis of the genome has been focused mainly on comparing differences, or ‘polymorphisms’, in the patterns of single letters in the chemical code for making and sustaining human life. But now, a group scientists from around the globe have come from a different angle and believe they have uncovered a complex, higher-order variation in the code.

This large difference in code between individuals can now explain why some people are vulnerable to certain diseases and respond well to certain drugs, while others fall sick quickly or never respond to treatment.

What the scientists have been doing is digging out deletions or duplications of code among relatively long sequences of individual DNA and then comparing these ‘copy number variations’ across a range of volunteers of diverse ancestry.

The researchers were stunned that they were able to locate 1447 copy number variations in nearly 2900 genes, which is about one eighth of the human genetic code.

Dr Matthew Hurles from the Wellcome Trust Sanger Institute in the UK is one of the project’s partners and says that “Each one of us has a unique pattern of gains and losses of complete sections of DNA. One of the real surprises of these results was just how much of our DNA varies in copy number. We estimate this to be at least 12% of the genome.”

The group found that almost 16% of genes that are known to be related to disease have these copy number variations. The diseases involved include rare genetic disorders like DiGeorge (caused by the deletion of a piece of chromosome number 22), Williams-Beuren (otherwise known as ‘Pixieism’) and Prader-Willi syndromes and those linked with schizophrenia, cataracts, spinal muscular atrophy and atherosclerosis.

But kidney disease, Parkinson’s, Alzheimer’s and vulnerability to malaria and HIV, which recent research has blamed on single-letter variations in the gene code, may also well be rooted in CNVs, the scientists believe.

Consequences of this recent research could benefit medical diagnosis and new drugs.

Aside: What is DNA?

DNA is a nucleic acid that contains the genetic instructions for the biological development of a cellular form of life or a virus. All known cellular life and some viruses have DNAs. DNA is a long polymer of nucleotides (a polynucleotide) that encodes the sequence of amino acid residues in proteins, using the genetic code.

DNA is responsible for the genetic propagation of most inherited traits. In humans, these traits range from hair color to disease susceptibility. The genetic information encoded by an organism’s DNA is called its genome.

http://www.youtube.com/watch?v=yQgcqtBICAU&feature=player_embedded

[I AM NOT THAT GUY 5,715]

This is science, right? I guess we need an organizer to move this thread to Off Topic.

P.S. Where is the link for your article?

[Danno 1,228]

P.S. Where is the link for your article?

Whoops, here is the link

http://www.articlesafari.com/2010/09/humans-not-genetically-identical/

[one...two...tree 2,762]

This article originated from Stormfront. It's not even science, but an interpretation of some research published from Nature.

It's funny that Danno would latch onto this.

[Danno 1,228]

This article originated from Stormfront. It's not even science, but an interpretation of some research published from Nature.

It's funny that Danno would latch onto this.

wow that was easy... because an artical was posted somewhere it can be dismissed without one bit of a counter argument.

So If I post the Constitution on the Daily Kos.... it too becomes worthless?

Steve as a big defender of "science"..... I would have expected more from you, if this article is misleading or even a fraud, please tell us how.

[one...two...tree 2,762]

wow that was easy... because an artical was posted somewhere it can be dismissed without one bit of a counter argument.

So If I post the Constitution on the Daily Kos.... it too becomes worthless?

Steve as a big defender of "science"..... I would have expected more from you, if this article is misleading or even a fraud, please tell us how.

The Human Genome Project is NOT assumed to be wrong. That's a fvcking lie by groups like Stormfront to try and validate why they think Blacks should be treated differently from Whites. If you want to buy into their propaganda bullsh!t, Danno, go ahead.

Now, if you really are interested in real science, here's some facts about the project:

The Human Genome Project (HGP) is an international scientific research project with a primary goal of determining the sequence of chemical base pairs which make up DNA and to identify and map the approximately 20,000–25,000 genes of the human genome from both a physical and functional standpoint.^[1]

The project began in 1990^[2] and was initially headed by James D. Watson at the U.S. National Institutes of Health. A working draft of the genome was released in 2000 and a complete one in 2003, with further, more detailed analysis still being published. A parallel project was conducted outside of government by the Celera Corporation. Most of the government-sponsored sequencing was performed in universities and research centers from the United States, the United Kingdom, Japan, France, Germany, China, India, Canada, and New Zealand. The mapping of human genes is an important step in the development of medicines and other aspects of health care.

While the objective of the Human Genome Project is to understand the genetic makeup of the human species, the project has also focused on several other nonhuman organisms such as E. coli, the fruit fly, and the laboratory mouse. It remains one of the largest single investigational projects in modern science.

.....

Key findings of the draft (2001) and complete (2004) genome sequences include^{[citation needed]}

1. There are approximately 19,000 genes in human beings, the same range as in mice and twice that of roundworms. Understanding how these genes express themselves will provide clues to how diseases are caused.^{[citation needed]}

2. Between 1.1% to 1.4% of the genome's sequence codes for proteins

3. The human genome has significantly more segmental duplications (near identical, repeated sections of DNA repeated) than other mammalian genomes. These sections may underlie the creation of new primate-specific genes

4. At the time when the draft sequence was published less than 7% of protein families appeared to be vertebrate specific.

http://en.wikipedia.org/wiki/Human_Genome_Project

[Danno 1,228]

The Human Genome Project is NOT assumed to be wrong. That's a fvcking lie by groups like Stormfront to try and validate why they think Blacks should be treated differently from Whites. If you want to buy into their propaganda bullsh!t, Danno, go ahead.

Now, if you really are interested in real science, here's some facts about the project:

Everything is about race with you, this has nothing to do with Stormfront for me it has everything to do with questioning certain aspects of "settled Science".

You know what I think?.... You don't respect research which comes from Asia... come on admit it.

[one...two...tree 2,762]

Everything is about race with you, this has nothing to do with Stormfront for me it has everything to do with questioning certain aspects of "settled Science".

You know what I think?.... You don't respect research which comes from Asia... come on admit it.

Where's the research, sparky? The original 'finding' that supposedly puts in question the Human Genome Project's findings? You're a gullible tool for propaganda like this.

[Danno 1,228]

Where's the research, sparky? The original 'finding' that supposedly puts in question the Human Genome Project's findings? You're a gullible tool for propaganda like this.

Another enemy of Science.

Steve do you really connect peoples "human worth" to where their ancestors might have originated?

[Danno 1,228]

Where's the research, sparky? The original 'finding' that supposedly puts in question the Human Genome Project's findings? You're a gullible tool for propaganda like this.

I Think your argument is with Dr Matthew Hurles from the Wellcome Trust Sanger Institute in the UK ... I don't think he is part of any racist websites.

Anyway, ... I'm just passin on the new findings in science to those who have an interest in new developments.

[Nina~ 431]

I read a few more articles by this "articlesafari" person and here are some of the Headlines:

Blue Eyes linked to Higer IQ

Descendants of Atlantis

Row Erupts over Casting Angeline Jolie as Cleopatra

Here are some of the reasons why you should realize that this is a fake science website:

1) Author's name is not mentioned in the article.

2) They never name who these "chinese scientists" are and what University they are affiliated with or anything about their research.

3) A real scientific research website would not care about the next Cleopatra movie.

[Danno 1,228]

I read a few more articles by this "articlesafari" person and here are some of the Headlines:

Blue Eyes linked to Higer IQ

Descendants of Atlantis

Row Erupts over Casting Angeline Jolie as Cleopatra

Here are some of the reasons why you should realize that this is a fake science website:

1) Author's name is not mentioned in the article.

2) They never name who these "chinese scientists" are and what University they are affiliated with or anything about their research.

3) A real scientific research website would not care about the next Cleopatra movie.

I hardly think this is the first or only website which takes information posted in Dry journals or news feeds and repackages it.

I'm heading out the door now but when I get back I might try to see if the quoted: "Dr Matthew Hurles from the Wellcome Trust Sanger Institute in the UK", is in fact legit.

Really the question is: is there any truth to it.... regardless of anything else?

[ready4ONE 5,400]

Everything is about race with you, this has nothing to do with Stormfront for me it has everything to do with questioning certain aspects of "settled Science".

You know what I think?.... You don't respect research which comes from Asia... come on admit it.

Awww Danno you are truly a wonder.

[Danno 1,228]

Awww Danno you are truly a wonder.

Hey... for some, if it doesn't come from Berkeley .........