From https://www.cdc.gov/immigrantrefugeehealth/exams/ti/panel/tuberculosis-panel-technical-instructions.html --
People with HIV infection are less likely to have an abnormal chest x-ray during tuberculosis disease; and negative IGRA results do not rule out tuberculosis disease, thus all applicants with known HIV infection must provide sputum specimens for microscopy and culture regardless of IGRA and chest x-ray results in order to rule out tuberculosis disease.