No, that is NOT it. Alien registration number will be if your wife or husband had come to the US previously and then should will have that. It is commonly known as the "A-Number". If they have not come here before, then you write "N/A" in that box.
She needede a new passport. The one she just got had het birth date all wrong. The interview itself was long 45 minutes but fair. We knew why they would need to ask these question. Might get visa end of this week.