Your mother is now a Legal Permanent Resident and will have to follow the steps to sponsor her brother just as you did to bring your mother here. The first step to bringing a sibling is to become a USC so she is eligible to sponsor her sibling. This falls into the fourth visa preference cateogry. If you view the current Visa Bulletin here
http://travel.state.gov/visa/frvi/bulletin...letin_3236.html you will see that fourth preference visas are now being processed from 08 JUN 1996. That means
after your mother becomes a USC and is eligible to file for her brother, the wait is ten + years.
On the issue of mentally-challenged applicants, in general I don't believe there are no special rules or provisions. However, you should be aware that some "mental disorders" make an applicant inadmissible and require a waiver. I don't know if this would impact your case. Other issues involving the cost for his care in the US may also come up.
http://www.travel.state.gov/visa/frvi/inel...ities_1364.html
Visa Ineligibilities:
have a physical or mental disorder and behavior associated with the disorder that may pose, or has posed, a threat to the property, safety, or welfare of the alien or others, or
(II) to have had a physical or mental disorder and a history of behavior associated with the disorder, which behavior has posed a threat to the property, safety, or welfare of the alien or others and which behavior is likely to recur or to lead to other harmful behavior, orExpedites of petitions and/or interviews are generally only available in the case of the USC's military deployment or severe medical condition. Requests for expedites are made directly to service centers or consulates. A senate immigration liaison can sometimes help faciliate the request if it falls under the service center or consulate's stated expedite requirements.
Your first step is to consult with a qualified immigration attorney be sure both you and your mother understand the process and any obstacles you might face (aside from the long wait).